According to Wile E. Coyote, Little Beeper appeared on Calamity's father's doorstep in the desert alongside Calamity, and the two of them have been given chase ever since. Soon, Calamity's father got a job offer in Acme Acres and both Calamity and Little Beeper moved there to continue the chase.
Little Beeper speaks mainly in sound effects (such as mimicking various musical instruments, sirens and other devices) and usually lets out the sounds of "meep, meep" (similar to Road Runner) or "beep, beep" (hence his name). He also laughs, yells and whistles, amongst other audible expressions, depending on his mood and situation, which usually involves Calamity but he never speaks out words.
Unlike Road Runner's typical bemusement at Wile E. Coyote's misfortunes, Little Beeper is often shown taking great joy at the sight of Calamity's failures; never passing up a chance to point and laugh at him. (It must, however, be noted, that Road Runner can be actually quite sadistic, e.g. knocking Wile E. off cliffs he spent ages climbing up). This attitude, however, has backfired on him more than once. In the worst scenario, in the Dating, Acme Acres Style episode segment, Love Stinks, Little Beeper ends up looking like a skunk and becomes the romantic target of Fifi La Fume. Poetic justice, perhaps, as Little Beeper spends that entire episode ridiculing Calamity, who had been in a similar (and smelly) situation.
In the Career Oppor-Toon-ities episode segment, Falling to Pizzas, Little Beeper is working during the summer for Bombino's Pizza restaurant, where this time Calamity actually wants to take and eat the pizza that Beeper is delivering instead of Beeper. According to Calamity's computer, roadrunners are very vain and cannot resist mirrors, which is proven as Beeper stops on his way delivering pizzas to stare at himself in an ACME mirror that Calamity placed in hopes to grab the pizza.
Little Beeper is a speed demon, a natural athlete, a bolt of lightning in tennis shoes. He is the fastest student at Acme Looniversity. His natural instincts always triumph over Calamity Coyote's cerebral schemes; what's more, his speed and grace make it seem easy...and he knows it. Like any good athlete, Little Beeper watches what he eats; unlike Calamity, who watches what he'd like to eat zoom off into the distance.
In the New Class Day episode segment, Just-Us League of Supertoons , Beeper is a member of the mighty superhero team, the Just-Us League of Supertoons. He is Little Dasher, a parody of Flash. This episode segment is one of the few where Little Beeper and Calamity Coyote (as Keen Arrow) work together, rather than against each other.